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Ethylenediaminetetraacetic acid

CAT: 0804-HY-Y0682-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-Y0682-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ethylenediaminetetraacetic acid (EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium) . Ethylenediaminetetraacetic acid has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research[1][2][3][4][5][6][7].
CAS Number
60-00-4
Product Name Alternative
EDTA
UNSPSC
12352200
Hazard Statement
H319, H402
Target
Bacterial; Biochemical Assay Reagents; SOD
Related Pathways
Anti-infection; Immunology/Inflammation; Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Neurological Disease; Cardiovascular Disease; Cancer
Purity
98.0
Solubility
0.1 M NaOH : 6.67 mg/mL (ultrasonic; warming; adjust pH to 7 with NaOH; heat to 60°C)
Smiles
O=C(O)CN(CCN(CC(O)=O)CC(O)=O)CC(O)=O
Molecular Formula
C10H16N2O8
Molecular Weight
292.24
Precautions
H319, H402
References & Citations
[1]Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412 (1) :34-9. |[2]Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 2007;45 (5) :565-76. |[3]Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb;10 (1) :58-62. |[4]Gray GW, et al. The effect of ethylenediaminetetra-acetic acid on the cell walls of some gram-negative bacteria. J Gen Microbiol. 1965 Jun;39 (3) :385-99. |[5]González-Cuevas J, et al. Ethylenediaminetetraacetic acid induces antioxidant and anti-inflammatory activities in experimental liver fibrosis. Redox Rep. 2011;16 (2) :62-70. |[6]Naghipour D, et al. Remediation of heavy metals contaminated silty clay loam soil by column extraction with ethylenediaminetetraacetic acid and nitrilo triacetic acid[J]. Journal of Environmental Engineering, 2017, 143 (8) : 04017026.|[7] Deai M, et al. Ethylenediaminetetraacetic acid (EDTA) enhances cAMP production in human TDAG8-expressing cells. Biochem Biophys Res Commun. 2022 Oct 20;626:15-20.
Shipping Conditions
Room Temperature
Storage Conditions
RT, protect from light, stored under nitrogen
Scientific Category
Biochemical Assay Reagents
Clinical Information
Launched
Citation 01
Adv Sci (Weinh) . 2023 Feb;10 (4) :e2204998.|Adv Sci (Weinh) . 2024 Dec 25:e2411261.|Adv Sci (Weinh) . 2025 Feb 8:e2415229.|Ann Med. 2025 Dec;57 (1) :2548045.|bioRxiv. 2023 Sep 8.|BMC Med Genomics. 2025 Aug 9;18 (1) :128.|Bone Res. 2025 Mar 3;13 (1) :30.|Cell Immunol. 2024 Jan-Feb:395-396:104781.|Colloids Surf B Biointerfaces. 2024 Feb:234:113680.|EMBO Mol Med. 2025 Oct 15.|Food Qual Saf. 2025 Aug 4.|Int J Biol Macromol. 2023 Jan 15:225:1182-1192.|Int J Biol Macromol. 2025 May 7:144068.|Int J Biol Macromol. 2026 Jan;335 (Pt 2) :149182.|J Extracell Vesicles. 2025 Sep;14 (9) :e70162.|J Nanobiotechnology. 2025 Mar 6;23 (1) :175.|J Orthop Surg Res. 2025 Apr 22;20 (1) :403.|Molecules. 2024 Jul 30;29 (15) :3590.|Nat Immunol. 2025 Oct;26 (10) :1660-1672.|Neuron. 2025 Jul 29:S0896-6273 (25) 00509-4.|Nucleic Acids Res. 2024 Nov 30:gkae1112.|Biomed Pharmacother. 2019 Jan:109:2427-2433.|Molecules. 2021 Aug 24;26 (17) :5115.|Research Square Preprint. 2021 Oct.|Environ Sci Technol. 2017 Dec 5;51 (23) :13938-13948.

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