Products for Research Use Only
RegisterLogin

CRBN ligand-561

CAT: 0804-HY-W953604Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W953604Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRBN ligand-561 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-561 can be linked to a target protein ligand via a linker to form a PROTAC.
CAS Number
2925095-98-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C1NC(=O)CCN1C=2C=CC3=CN(N=C3C2)CCN
Molecular Formula
C13H15N5O2
Molecular Weight
273.30
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Chemical Information

1-[2-(2-aminoethyl)-2H-indazol-6-yl]-1,3-diazinane-2,4-dione
CAS Number2925095-98-1
PubChem CID169548660
IUPAC Name1-[2-(2-aminoethyl)indazol-6-yl]-1,3-diazinane-2,4-dione
Molecular FormulaC13H15N5O2
Molecular Weight273.29
XLogP-0.8
Topological Polar Surface Area93.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Heavy Atom Count20
Formal Charge0
Complexity402
SMILES
C1CN(C(=O)NC1=O)C2=CC3=NN(C=C3C=C2)CCN
InChI
InChI=1S/C13H15N5O2/c14-4-6-17-8-9-1-2-10(7-11(9)16-17)18-5-3-12(19)15-13(18)20/h1-2,7-8H,3-6,14H2,(H,15,19,20)
InChIKey
KHEZQVVVTQJGJC-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-[2-(2-aminoethyl)-2H-indazol-6-yl]-1,3-diazinane-2,4-dione
CAS: 2925095-98-1
CID: 169548660
Formula: C13H15N5O2
MW: 273.29
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight273.29
XLogP3-0.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count3
Exact Mass273.12257474
Monoisotopic Mass273.12257474
Topological Polar Surface Area93.3 Ų
Heavy Atom Count20
Formal Charge0
Complexity402
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-179733CRBN ligand-191
HY-169989-01CRBN ligand-11
HY-171224CRBN ligand-45
HY-170213CRBN ligand-183
HY-170108CRBN ligand-47
HY-170075CRBN ligand-16
HY-W999738CRBN ligand-834
HY-W999733CRBN ligand-832
HY-W999729CRBN ligand-851
HY-W999717CRBN ligand-282

Alternative Products

CatalogName
GTR19276477-01CRBN ligand-561
T205631-01CRBN ligand-112
T205588-01CRBN ligand-110
T205577-01CRBN ligand-45
T205145-01CRBN ligand-47
T9360-01CRBN ligand-9
GTR19249891-01CRBN ligand-16
GTR19249567-01CRBN ligand-148
GTR19249350-01CRBN ligand-14
GTR19249319-01CRBN ligand-164

Popular Products