Senkyunolide B

• Description :

  Senkyunolide B is a phthalide found in Angelica sinensis. Senkyunolide B has broad antifungal activities. Senkyunolide B affects the spore germination and hyphae growth of Aspergillus fumigatus via down-regulating phosphatidylinositol-PKC-calcineurin axis and the expression of ENG genes[1].

• CAS Number :

  [93236-67-0]

• UNSPSC :

  12352005

• Target :

  Calcineurin; Fungal; PKC

• Related Pathways :

  Anti-infection; Epigenetics; Neuronal Signaling; TGF-beta/Smad

• Field of Research :

  Infection

• Smiles :

  O=C(C1=C(C=CC=C1/2)O)OC2=C/CCC

• Molecular Formula :

  C12H12O3

• Molecular Weight :

  204.22

• References & Citations :

  [1]Tan J, et al. Senkyunolide B exhibits broad-spectrum antifungal activity against plant and human pathogenic fungi via inhibiting spore germination and destroying the mature biofilm. Pest Manag Sci. 2023 Dec;79 (12) :4952-4963.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported