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Senkyunolide B

CAT: 0804-HY-W782599-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W782599-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Senkyunolide B is a phthalide found in Angelica sinensis. Senkyunolide B has broad antifungal activities. Senkyunolide B affects the spore germination and hyphae growth of Aspergillus fumigatus via down-regulating phosphatidylinositol-PKC-calcineurin axis and the expression of ENG genes[1].
CAS Number
93236-67-0
UNSPSC
12352005
Target
Calcineurin; Fungal; PKC
Related Pathways
Anti-infection; Epigenetics; Neuronal Signaling; TGF-beta/Smad
Field of Research
Infection
Smiles
O=C(C1=C(C=CC=C1/2)O)OC2=C/CCC
Molecular Formula
C12H12O3
Molecular Weight
204.22
References & Citations
[1]Tan J, et al. Senkyunolide B exhibits broad-spectrum antifungal activity against plant and human pathogenic fungi via inhibiting spore germination and destroying the mature biofilm. Pest Manag Sci. 2023 Dec;79 (12) :4952-4963.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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