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2,5-Deoxyfructosazine-13C4

CAT: 0804-HY-W777675-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W777675-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2,5-Deoxyfructosazine-13C4 (NSC 270912-13C4) is the 13C-labeled 2,5-Deoxyfructosazine. 2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
CAS Number
1246815-27-9
Product Name Alternative
NSC 270912-13C4
UNSPSC
12352005
Target
DNA/RNA Synthesis; Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Others
Smiles
OC[C@@H](O)[C@@H](O)[C@H](O)[13C]1=N[13CH]=[13C](C[C@H](O)[C@H](O)CO)N=[13CH]1
Molecular Formula
C8 13C4H20N2O7
Molecular Weight
308.27
References & Citations
[1]Henry, et al. Synthesis of water-compatible imprinted polymers of in situ produced fructosazine and 2,5-deoxyfructosazine. Talanta 99, 816-823 (2012) .
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported