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2,5-Deoxyfructosazine

CAT: 0804-HY-135078-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-135078-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM) .
CAS Number
17460-13-8
Product Name Alternative
NSC 270912
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-5-deoxyfructosazine.html
Smiles
O[C@H](C1=NC=C(C[C@H](O)[C@H](O)CO)N=C1)[C@H](O)[C@H](O)CO
Molecular Formula
C12H20N2O7
Molecular Weight
304.30
References & Citations
[1]Henry, et al. Synthesis of water-compatible imprinted polymers of in situ produced fructosazine and 2,5-deoxyfructosazine. Talanta 99, 816-823 (2012) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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