2-Formyl sunitinib

• Description:

  2-Formyl sunitinib (1-CHO) is a metabolite of tyrosine kinase inhibitor Sunitinib (HY-10255A) . 2-Formyl sunitinib can be used for the research of cancer[1].

• UNSPSC:

  12352005

• Target:

  Drug Metabolite

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  O=C(/C(C1=C2)=C\C3=C(C(C(NCCN(CC)CC)=O)=C(N3)C=O)C)NC1=CC=C2F

• Molecular Formula:

  C22H25FN4O3

• Molecular Weight:

  412.46

• References & Citations:

  [1]Paludetto MN, et al. Metalloporphyrin-Catalyzed Oxidation of Sunitinib and Pazopanib, Two Anticancer Tyrosine Kinase Inhibitors: Evidence for New Potentially Toxic Metabolites. J Med Chem. 2018 Sep 13;61 (17) :7849-7860.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2377533-92-9