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Flunisolide-d4

CAT: 0804-HY-W752724Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W752724Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Flunisolide-d4 is the deuterium labeled Flunisolide (HY-B1121) . Flunisolide is a corticosteroid, which is an orally active glucocorticoid receptor activator with anti-inflammatory activity. Flunisolide can induce eosinophil apoptosis, and is used for the research of asthma or rhinitis, and inflammation[1][2].
UNSPSC
12352211
Target
Apoptosis; Glucocorticoid Receptor; Isotope-Labeled Compounds
Related Pathways
Apoptosis; Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Endocrinology; Inflammation/Immunology
Smiles
O=C1C=C[C@@]2(C([C@H](C[C@@]3([C@@]2([C@]([2H])(C[C@]4([C@@]3(C[C@@]5([C@]4(CCC5)C(C([2H])([2H])O)=O)[H])[H])C)O)[2H])[H])F)=C1)C
Molecular Formula
C24H27D4FO4
Molecular Weight
406.52
References & Citations
[1]Tatiana Paula Teixeira Ferreira, et al. Intranasal Flunisolide Suppresses Pathological Alterations Caused by Silica Particles in the Lungs of Mice. Front Endocrinol (Lausanne) . 2020 Jun 17;11:388. |[2]M Profita, et al. In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics. Allergy. 2004 Sep;59 (9) :927-32.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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