Immucillin-G

• Description :

  Immucillin-G is a purine nucleoside phosphorylase (PNP) inhibitor. Immucillin-G can reduce urate levels and can be used for the research of metabolic disease, such as hyperuricemia[1].

• CAS Number :

  [209799-75-7]

• UNSPSC :

  12352005

• Target :

  Nucleoside Antimetabolite/Analog

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Metabolic Disease

• Smiles :

  O=C1C(NC=C2[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)=C2N=C(N)N1

• Molecular Formula :

  C11H15N5O4

• Molecular Weight :

  281.27

• References & Citations :

  [1]Jacomelli G, et al. Inhibiting PNP for the therapy of hyperuricemia in Lesch-Nyhan disease: Preliminary in vitro studies with analogues of immucillin-G. J Inherit Metab Dis. 2019 Jan;42 (1) :178-185.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported