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Sarcosine-13C3

CAT: 0804-HY-W748519-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W748519-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sarcosine-13C3 (N-Methylglycine-13C3; Sarcosin-13C3) is the 13C-labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
CAS Number
2806125-84-6
Product Name Alternative
N-Methylglycine-13C3; Sarcosin-13C3
UNSPSC
12352211
Target
Endogenous Metabolite; GlyT; Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Cancer
Smiles
O[13C]([13C]([H])(N[13CH3])[H])=O
Molecular Formula
13C3H7NO2
Molecular Weight
92.07
References & Citations
[1]Katarzyna Socała, et al. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Pharmacol Rep. Mar-Apr 2010;62 (2) :392-7.|[2]Mei-Yi Lee, et al. Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials. J Biomed Sci. 2017; 24: 18.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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