Products for Research Use Only
RegisterLogin

Sarcosine-d3

CAT: 0804-HY-101037S1-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-101037S1-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Sarcosine-d3 is the deuterium labeled Sarcosine. Sarcosine (N-Methylglycine), an endogenous amino acid, is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist. Sarcosine increases the glycine concentration, resulting in an indirect potentiation of the NMDA receptor. Sarcosine is commonly used for the research of schizophrenia[1][2].
CAS Number
118685-91-9
Product Name Alternative
N-Methylglycine-d3; Sarcosin-d3
UNSPSC
12352211
Hazard Statement
H302, H312, H332
Target
Endogenous Metabolite; GlyT; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.05
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
O=C(O)CNC([2H])([2H])[2H]
Molecular Formula
C3H4D3NO2
Molecular Weight
92.11
Precautions
H302, H312, H332
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Katarzyna Socała, et al. Effects of sarcosine, a glycine transporter type 1 inhibitor, in two mouse seizure models. Pharmacol Rep. Mar-Apr 2010;62 (2) :392-7.|[3]Mei-Yi Lee, et al. Effects of sarcosine and N, N-dimethylglycine on NMDA receptor-mediated excitatory field potentials. J Biomed Sci. 2017; 24: 18.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
GlyT1

Related Products

CatalogName
HY-101037-01Sarcosine
HY-101037R-01Sarcosine (Standard)
HY-101037S-01Sarcosine-15N
HY-W748519-01Sarcosine-13C3
HY-P2861Sarcosine oxidase, Bacillus
HY-Y1144-01Sarcosine ethyl ester hydrochloride
HY-P702177-01Monomeric sarcosine oxidase, Bacillus sp.
HY-15398S3-01Vitamin D3-d3
HY-P702178Monomeric sarcosine oxidase, Bacillus sp. (His)
HY-132348S1Granisetron-d3 (1-methyl-d3)

Alternative Products

CatalogName
465874-01Sarcosine-d3
sc-229281Sarcosine-d3 (methyl-d3)
sc-212914Sarcosine-d3 Hydrochloride
465875-01Sarcosine-d3 t-Butyl Ester TFA Salt
B3116-5GSarcosine

Popular Products