Dimethyl tetrasulfide

• Description:

  Dimethyl tetrasulfide (1,4-Dimethyltetrasulfane) is an apoptosis inducer targeting leukemia cells. Dimethyl tetrasulfide exerts cytotoxic effects through the induction of intracellular reactive oxygen species (ROS) production and activation of caspase-3 enzyme. Dimethyl tetrasulfide is promising for research of cancers, such as leukemia[1][2].

• Product Name Alternative:

  1,4-Dimethyltetrasulfane

• UNSPSC:

  12352100

• Hazard Statement:

  H302

• Target:

  Apoptosis; Caspase; Reactive Oxygen Species (ROS)

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Cancer

• Smiles:

  CSSSSC

• Molecular Formula:

  C2H6S4

• Molecular Weight:

  158.33

• Precautions:

  P264-P270-P330-P501

• References & Citations:

  [1]Moon HI. Larvicidal activity of major essential oils from stems of Allium monanthum Maxim. against Aedes aegypti L. J Enzyme Inhib Med Chem. 2011 Dec;26 (6) :827-30.|[2]Zhang G, et al. Effect of dimethyl sulfides on the induction of apoptosis in human leukemia Jurkat cells and HL-60 cells. Biosci Biotechnol Biochem. 2008 Nov;72 (11) :2966-72.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  5756-24-1