Dimethyl phthalate

• Description :

  Dimethyl phthalate (DMP) can be used as a plasticizer to impart flexibility to rigid polyvinyl chloride (PVC) resin. Additionally, Dimethyl phthalate is an oral active endocrine disruptor that can cause ovarian dysfunction in mice. Dimethyl phthalate can also induce oxidative stress and apoptosis in cells, thereby affecting blood and red blood cell function in rats[1].

• Product Name Alternative :

  DMP

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Apoptosis; Biochemical Assay Reagents; Reactive Oxygen Species (ROS)

• Type :

  Natural Products

• Related Pathways :

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/dimethyl-phthalate.html

• Purity :

  99.87

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(C1=CC=CC=C1C(OC)=O)OC

• Molecular Formula :

  C10H10O4

• Molecular Weight :

  194.19

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Wang ZG, et al. Impacts of dimethyl phthalate on the bacterial community and functions in black soils. Front Microbiol. 2015 May 5;6:405.|[2]Kara M, et al. Investigation of the Neurotoxic Effects of Dimethyl Phthalate and Diisobutyl Phthalate on SH-SY5Y Neuroblastoma Cells[J]. Recent Trends in Pharmacology, 2024, 2 (3) : 101-108.|[3]Wang Z, et al. Dimethyl phthalate damaged the cell membrane of Escherichia coli K12. Ecotoxicol Environ Saf. 2019 Sep 30;180:208-214.|[4]Chi Z, et al. Revealing the toxicity of dimethyl phthalate (DMP) to the oxygen-carrying function of red blood cells (RBCs) : The iron release mechanism. Chemosphere. 2021 Jan;263:128017.|[5]Mei Y, et al. Effects of Dimethyl Phthalate (DMP) on Serum Sex Hormone Levels and Apoptosis in C57 Female Mice. Int J Endocrinol Metab. 2019 Apr 22;17 (2) :e82882.|[6]Yin H, et al. Dimethyl phthalate exposure induces cognitive impairment via COX2-mediated neuroinflammation. Ecotoxicol Environ Saf. 2024 Oct 1;284:117039.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  RT, protect from light

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [131-11-3]