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7-Hydroxychlorpromazine (hydrochloride)

CAT: 0804-HY-W704749-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-W704749-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
7-Hydroxychlorpromazine hydrochloride is the active metabolite of Chlorpromazine. 7-Hydroxychlorpromazine hydrochloride can increase prolactin levels in rats. 7-Hydroxychlorpromazine hydrochloride can increase dopamine turnover and has a sedative effect. In addition, 7-Hydroxychlorpromazine hydrochloride can effectively inhibit amphetamine-induced stereotyped behavior in rats and is used in the study of psychosis[1][2].
CAS Number
51938-11-5
UNSPSC
12352005
Hazard Statement
H301-H330
Target
Dopamine Receptor; Drug Metabolite
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
ClC1=CC=C2SC3=CC(O)=CC=C3N(CCCN(C)C)C2=C1.Cl
Molecular Formula
C17H20Cl2N2OS
Molecular Weight
371.32
Precautions
P260-P264-P270-P271-P284-P304+P340-P330-P403+P233-P405-P501
References & Citations
[1]Meltzer H Y, et al. Effect of metabolites of chlorpromazine on plasma prolactin levels in male rats[J]. European Journal of Pharmacology, 1977, 41 (4) : 431-436.|[2]Perry T L, et al. 7-Hydroxychlorpromazine: potential toxic drug metabolite in psychiatric patients[J]. Science, 1964, 146 (3640) : 81-83.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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