HCV-IN-7 (hydrochloride)

HCV-IN-7 (hydrochloride)

• CAS Number: 1449756-87-9
• UNSPSC Description: HCV-IN-7 hydrochloride is an orally active and potent pan-genotypic HCV NS5A inhibitor with IC50s of 3-47 pM. HCV-IN-7 hydrochloride shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake. HCV-IN-7 hydrochloride has anti-viral activity[1].
• Target Antigen: HCV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/hcv-in-7-hydrochloride.html
• Solubility: 10 mM in DMSO
• Smiles: [H]Cl.[H]Cl.O=C([C@H](C(C)C)NC(OC)=O)N(CCC1)[C@@H]1C(N2)=NC=C2C3=CC(C=C4)=C(S3)C5=C4C=C(C6=CN=C([C@H]7N(C([C@H](C(C)C)NC(OC)=O)=O)CCC7)N6)C=C5
• Molecular Weight: 841.85
• References & Citations: [1]Ramdas V, et al. Discovery and Characterization of Potent Pan-Genotypic HCV NS5A Inhibitors Containing Novel Tricyclic Central Core Leading to Clinical Candidate. J Med Chem. 2019 Dec 12;62(23):10563-10582.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported