Fenhexamid-d10

• Description :

  Fenhexamid-d10 is the deuterium labeled Fenhexamid (HY-118065) . Fenhexamid, a botryticide, is a sterol biosynthesis inhibitor. Fenhexamid shows fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) [1].

• UNSPSC :

  12352005

• Target :

  Estrogen Receptor/ERR; Fungal; Isotope-Labeled Compounds; PI3K

• Related Pathways :

  Anti-infection; Others; PI3K/Akt/mTOR; Vitamin D Related/Nuclear Receptor

• Field of Research :

  Cancer

• Smiles :

  OC1=CC=C(C(Cl)=C1Cl)NC(C2(C([2H])(C([2H])(C([2H])(C([2H])(C2([2H])[2H])[2H])[2H])[2H])[2H])C)=O

• Molecular Formula :

  C14H7D10Cl2NO2

• Molecular Weight :

  312.26

• References & Citations :

  [1]Debieu D, et al. The hydroxyanilide fenhexamid, a new sterol biosynthesis inhibitor fungicide efficient against the plant pathogenic fungus Botryotinia fuckeliana (Botrytis cinerea) . Pest Manag Sci. 2001 Nov;57 (11) :1060-7.|[2]Go RE, et al., Effect of fenhexamid and cyprodinil on the expression of cell cycle- and metastasis-related genes via an estrogen receptor-dependent pathway in cellular and xenografted ovarian cancer models. Toxicol Appl Pharmacol. 2015 Nov 15;289 (1) :48-57.|[3]Medjakovic S, et al., Effect of nonpersistent pesticides on estrogen receptor, androgen receptor, and aryl hydrocarbon receptor. Environ Toxicol. 2014 Oct;29 (10) :1201-16.|[4]Go RE, et al., A fungicide, fenhexamid, is involved in the migration and angiogenesis in breast cancer cells expressing estrogen receptors. Life Sci. 2022 Sep 15;305:120754.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1246815-53-1]