IMPDH-IN-2

• Description :

  IMPDH-IN-2 (compound 2) is an inhibitor of inosine monophosphate dehydrogenase (IMPDH) with IC50Values are 0.15 and 0.17 μM, respectively. IMPDH-IN-2 has antitumor activity[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  IMPDH

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Purity :

  98.95

• Smiles :

  CC1=C(C(C/C=C(CCC(O)=O)\C)=C(C2=C1COC2=O)O)O

• Molecular Formula :

  C16H18O6

• Molecular Weight :

  306.31

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1] Mitsuhashi S, et al. Structure-activity relationships for inhibition of inosine monophosphate dehydrogenase and differentiation induction of K562 cells among the mycophenolic acid derivatives. Bioorg Med Chem. 2010 Nov 15;18 (22) :8106-11.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [31858-65-8]