4-Hydroxy valsartan

• Description:

  4-Hydroxy valsartan is a metabolite of Valsartan (HY-18204) . 4-Hydroxy valsartan regulates the expression of platelet surface receptors and inhibits conventional plasma or whole blood collagen induced platelet aggregation. 4-Hydroxy valsartan has antiplatelet activity[1].

• Product Name Alternative:

  Valeryl-4-hydroxyvalsartan; CGP 71580

• UNSPSC:

  12352005

• Target:

  Drug Metabolite

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C(N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NN=NN3)[C@@H](C(C)C)C(O)=O)CCC(C)O

• Molecular Formula:

  C24H29N5O4

• Molecular Weight:

  451.52

• References & Citations:

  [1]Serebruany VL, et al. Effects of valsartan and valeryl 4-hydroxy valsartan on human platelets: a possible additional mechanism for clinical benefits. J Cardiovasc Pharmacol. 2004 May;43 (5) :677-84.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [188259-69-0]