P131

• Description:

  P131 is a PROTAC molecule comprised of Pomalidomide-based cereblon ligand and IBT6A, linked by a PEG 3 chain. P131 can degrade both wild-type and C481S mutant BTK with nanomolar potencies.

• UNSPSC:

  12352005

• Target:

  PROTAC Linkers

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Smiles:

  NC1=NC=NC2=C1C(C3=CC=C(C=C3)OC4=CC=CC=C4)=NN2[C@@H]5CCCN(C5)C(C6=CN(N=N6)CCOCCOCCOCCNC7=C8C(N(C(C8=CC=C7)=O)C9CCC(NC9=O)=O)=O)=O

• Molecular Formula:

  C46H48N12O9

• Molecular Weight:

  912.95

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2360561-66-4]