12-Tridecenoic acid

• Description :

  12-Tridecenoic acid is a metabolite of intestinal flora, which can promote the expression of acetyl-CoA carboxylase α (ACC) and inhibit the expression of carnitine palmitoyltransferase 1A (CPT1A), thereby aggravating hepatic steatosis. 12-Tridecenoic acid aggravates hepatic steatosis by affecting the ACC-CPT1A axis[1].

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H312, H332

• Target :

  Acetyl-CoA Carboxylase; Endogenous Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Purity :

  95.0

• Smiles :

  C=CCCCCCCCCCCC(O)=O

• Molecular Formula :

  C13H24O2

• Molecular Weight :

  212.33

• Precautions :

  H302, H312, H332

• References & Citations :

  [1]Xu R, et al. Gan-jiang-ling-zhu decoction improves steatohepatitis by regulating gut microbiota-mediated 12-tridecenoic acid inhibition. Front Pharmacol. 2024 Aug 23;15:1444561.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [6006-06-0]