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Fructose-phenylalanine

CAT: 0804-HY-W585934-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W585934-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Fructose-phenylalanine (Fru-Phe) is a non-competitive angiotensin-converting enzyme (ACE) inhibitor (IC50 =0.19 mM) with antioxidant activities. Fructose-phenylalanine forms a stable complex with Zn2+ ions at the ACE active site, blocking the conversion of angiotensin I to II and thereby lowering blood pressure. Fructose-phenylalanine is promising for research of cardiovascular diseases[1][2].
CAS Number
31105-03-0
Product Name Alternative
Fru-Phe
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Angiotensin-converting Enzyme (ACE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
OC[C@@H](O)[C@@H](O)[C@H](O)C(CN[C@H](C(O)=O)CC1=CC=CC=C1)=O
Molecular Formula
C15H21NO7
Molecular Weight
327.33
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Johnson GH, et al. Nutritional implications of the Maillard reaction: the availability of fructose-phenylalanine to the chick. J Nutr. 1977 Sep;107 (9) :1659-64.|[2]Jiahao Yu, et al. Potential contribution of Amadori compounds to antioxidant and angiotensin I converting enzyme inhibitory activities of raw and black garlic. LWT, Volume 129, 2020, 109553, ISSN 0023-6438
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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