Probucol dithiobisphenol

CAT: 0804-HY-W424839Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-W424839Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Probucol dithiobisphenol (DTBP) is the derivative of Probucol (HY-B0388) . Probucol dithiobisphenol induces the production of heme oxygenase 1 (HO-1), and exhibits antioxidant activity. Probucol dithiobisphenol inhibits atherosclerotic lesions in Apoe−/− mice aorta, promotes re-endothelialization of aorta and inhibits restenosis in rabbit arterial injury models. Probucol dithiobisphenol is orally active[1].
CAS Number
[6386-58-9]
Product Name Alternative
DTBP
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Heme Oxygenase (HO)
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SSC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C
Molecular Formula
C28H42O2S2
Molecular Weight
474.76
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Wu BJ, et al., Antioxidants protect from atherosclerosis by a heme oxygenase-1 pathway that is independent of free radical scavenging. J Exp Med. 2006 Apr 17;203 (4) :1117-27.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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