Probucol dithiobisphenol

• Target:

  ROS

• Related Pathways:

  Immunology/Inflammation

• Bioactivity:

  Probucoldithiobisphenol (DTBP) is a derivative of Probucol. It stimulates the production of heme oxygenase 1 (HO-1) and exhibits antioxidant properties. In the Apoe?/? mouse model, Probucol dithiobisphenol reduces aortic atherosclerotic lesions, and in a rabbit arterial injury model, it promotes arterial re-endothelialization and suppresses restenosis. This compound is orally active.

• Smiles:

  OC=1C(=CC(SSC=2C=C(C(O)=C(C2)C(C)(C)C)C(C)(C)C)=CC1C(C)(C)C)C(C)(C)C

• Molecular Formula:

  C28H42O2S2

• Molecular Weight:

  474.762

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  6386-58-9