Products for Research Use Only
RegisterLogin

CRBN ligand-661

CAT: 0804-HY-W244823-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-W244823-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CRBN ligand-661 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-661 can be linked to a target protein ligand via a linker to form a PROTAC.
CAS Number
2154343-24-3
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Purity
98.73
Smiles
O=C1NC(=O)C(N2C(=O)C3=CC=C(Cl)N=C3C2)CC1
Molecular Formula
C12H10ClN3O3
Molecular Weight
279.68
Precautions
H301, H311, H331
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
Cereblon

Chemical Information

3-(2-chloro-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)piperidine-2,6-dione
CAS Number2154343-24-3
PubChem CID132117718
IUPAC Name3-(2-chloro-5-oxo-7H-pyrrolo[3,4-b]pyridin-6-yl)piperidine-2,6-dione
Molecular FormulaC12H10ClN3O3
Molecular Weight279.68
XLogP0.1
Topological Polar Surface Area79.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count19
Formal Charge0
Complexity442
SMILES
C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC(=N3)Cl
InChI
InChI=1S/C12H10ClN3O3/c13-9-3-1-6-7(14-9)5-16(12(6)19)8-2-4-10(17)15-11(8)18/h1,3,8H,2,4-5H2,(H,15,17,18)
InChIKey
DHBLCYUMZORRJD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 3-(2-chloro-5-oxo-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)piperidine-2,6-dione
CAS: 2154343-24-3
CID: 132117718
Formula: C12H10ClN3O3
MW: 279.68
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight279.68
XLogP30.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass279.0410689
Monoisotopic Mass279.0410689
Topological Polar Surface Area79.4 Ų
Heavy Atom Count19
Formal Charge0
Complexity442
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-179733CRBN ligand-191
HY-169989-01CRBN ligand-11
HY-171224CRBN ligand-45
HY-170213CRBN ligand-183
HY-170108CRBN ligand-47
HY-170075CRBN ligand-16
HY-W999738CRBN ligand-834
HY-W999733CRBN ligand-832
HY-W999729CRBN ligand-851
HY-W999717CRBN ligand-282

Alternative Products

CatalogName
GTR19277015-01CRBN ligand-661
T205631-01CRBN ligand-112
T205588-01CRBN ligand-110
T205577-01CRBN ligand-45
T205145-01CRBN ligand-47
T9360-01CRBN ligand-9
GTR19249891-01CRBN ligand-16
GTR19249567-01CRBN ligand-148
GTR19249350-01CRBN ligand-14
GTR19249319-01CRBN ligand-164

Popular Products