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2,5-Dimethylcyclohexanol

CAT: 0804-HY-W160358Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W160358Size:1 Each
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Description
2,5-Dimethylcyclohexanol, a volatile organic compound, is a fatty acid that can be isolated from Amphora sp.. 2,5-Dimethylcyclohexanol has significant antineoplastic and antiviral activities with inhibition of SARS-CoV-2 Mpro. 2,5-Dimethylcyclohexanol also has potent antifungal activity against Pseudogymnoascus destructans. 2,5-Dimethylcyclohexanol compromises cell wall and membrane integrity while perturbing energy metabolism, increases the levels of ROS, ATP, Superoxide anion and GSH, and decreases CAT and SOD activities. And 2,5-Dimethylcyclohexanol alters virulence ribosomal genes expression, and disrupts the MAPK signaling pathways, inducing fungal cell apoptosis[1][2][3].
CAS Number
3809-32-3
UNSPSC
12352211
Hazard Statement
H227-H302
Target
Apoptosis; ATP Synthase; Fungal; Glutathione Peroxidase; p38 MAPK; Reactive Oxygen Species (ROS) ; SARS-CoV; SOD; Virus Protease
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer; Infection
Smiles
CC1CCC(C)C(C1)O
Molecular Formula
C8H16O
Molecular Weight
128.21
Precautions
P210-P264-P270-P280-P330-P370+P378-P403-P501
References & Citations
[1]Khumaidi A, et al. Fatty acid profile and in silico pharmacological study of diatom Amphora sp[J]. Aquaculture, Aquarium, Conservation & Legislation, 2020, 13 (4) : 2050-2060.|[2]Huang Z, et al. Mechanisms of volatile organic compounds from bat cave environments against Pseudogymnoascus destructans in vitro. Appl Environ Microbiol. 2025 Nov 13:e0118725. |[3]Shehzadi S, et al. Antiviral COVID-19 protein and molecular docking: In silico characterization of various antiviral compounds extracted from Arisaema jacquemontii Blume. Front Public Health. 2022 Sep 23;10:964741.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
Phase 1

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