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3-Phenylthiophene

CAT: 0804-HY-W140208-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W140208-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3-Phenylthiophene (Compound 25) is a CYP2A6 inhibitor with a Ki value of 3.3 μM. The Ki values for CYP2E1, CYP2B6, CYP2C9, and CYP2C19 are 9.7, 14, 112, and 107 μM respectively. It shows no significant inhibition on CYP3A4 and CYP2D6. 3-Phenylthiophene can be used in smoking cessation research[1].
CAS Number
2404-87-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
95.0
Smiles
S1C=CC(=C1)C2=CC=CC=C2
Molecular Formula
C10H8S
Molecular Weight
160.23
Precautions
H302, H315, H319, H335
References & Citations
[1]Yano JK, et al. Synthetic inhibitors of cytochrome P-450 2A6: inhibitory activity, difference spectra, mechanism of inhibition, and protein cocrystallization. J Med Chem. 2006 Nov 30;49 (24) :6987-7001.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Isoform
CYP2; CYP3

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