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Thalidomide-O-amido-PEG2-Mal

CAT: 0804-HY-W1130394Size: 1 EachDry Ice: NoHazardous: No
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Description
Thalidomide-O-amido-PEG2-Mal is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-O-amido-PEG2-Mal can be linked to a target protein ligand via a linker to form a PROTAC.
UNSPSC
12352005
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(NCCOCCOCCN1C(C=CC1=O)=O)COC2=C3C(N(C(C3=CC=C2)=O)C4CCC(NC4=O)=O)=O
Molecular Formula
C25H26N4O10
Molecular Weight
542.49
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

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