Thalidomide-O-amido-PEG2-C2-NH2 (TFA)

Thalidomide-O-amido-PEG2-C2-NH2 (TFA)

• CAS Number: 1957235-75-4
• UNSPSC Description: Thalidomide-O-amido-PEG2-C2-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology.
• Target Antigen: Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: Apoptosis;Autophagy;PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/E3_Ligase_Ligand-Linker_Conjugates_24_TFA.html
• Purity: 99.72
• Solubility: DMSO : 100 mg/mL (ultrasonic)|H2O : 150 mg/mL (ultrasonic)
• Smiles: O=C(NCCOCCOCCN)COC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O.O=C(O)C(F)(F)F
• Molecular Weight: 576.48
• References & Citations: [1]ARYL SULFONOHYDRAZIDES. WO 2017/176958 A1.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported