Xipamide-d6

• Description :

  Xipamide-d6 is the deuterium labeled Xipamide. Xipamide is a sulfonamide-based diuretic. Xipamide is an antihypertensive agent able to selectively inhibit the anion exchanger (AE) [1][2].

• CAS Number :

  [1330262-09-3]

• UNSPSC :

  12352005

• Target :

  Isotope-Labeled Compounds

• Related Pathways :

  Others

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Solubility :

  10 mM in DMSO

• Smiles :

  C(NC1=C(C([2H])([2H])[2H])C=CC=C1C([2H])([2H])[2H])(=O)C2=CC(S(N)(=O)=O)=C(Cl)C=C2O

• Molecular Formula :

  C15H9D6ClN2O4S

• Molecular Weight :

  360.85

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Prichard BN, et al. Xipamide. A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy. Drugs. 1985 Oct;30 (4) :313-32.|[3]Hannaert P, et al. Beneficial effects of xipamide on pH and Ca2+ ions of cardiac cells. Arch Mal Coeur Vaiss. 1990 Jul;83 (8) :1271-4.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported