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Ac4GlcNAz

CAT: 0804-HY-W039953-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W039953-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC) . It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu (I) -catalyzed azide-alkyne cycloaddition conditions.
CAS Number
98924-81-3
Product Name Alternative
N-azidoacetylglucosamine-tetraacylated
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Others
Purity
99.60
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC(O[C@@H]1[C@H](C(O[C@@H]([C@H]1OC(C)=O)COC(C)=O)OC(C)=O)NC(CN=[N+]=[N-])=O)=O
Molecular Formula
C16H22N4O10
Molecular Weight
430.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Luong P, Ghosh A, Moulton KD, Kulkarni SS, Dube DH. Synthesis and Application of Rare Deoxy Amino l-Sugar Analogues to Probe Glycans in Pathogenic Bacteria. ACS Infect Dis. 2022 Apr 8;8 (4) :889-900. |[2]Clark EL, Emmadi M, Krupp KL, Podilapu AR, Helble JD, Kulkarni SS, Dube DH. Development of Rare Bacterial Monosaccharide Analogs for Metabolic Glycan Labeling in Pathogenic Bacteria. ACS Chem Biol. 2016 Dec 16;11 (12) :3365-3373.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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