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Bromodichloromethane

CAT: 0804-HY-W019780Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-W019780Size:1 Each
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Description
Bromodichloromethane (Dichlorobromomethane) is a type of trihalomethane, commonly found in chlorinated drinking water for disinfection, and is a disinfection by-product. The bromination of bromodichloromethane can cause the formation of mutagenic intermediates through the transformation mediated by glutathione S-transferase (GST) . Bromodichloromethane inhibits the differentiation of human placental trophoblast cells and reduces the secretion of chorionic gonadotropin (CG) . Bromodichloromethane has potential reproductive toxicity and carcinogenicity[1][2].
CAS Number
75-27-4
Product Name Alternative
Dichlorobromomethane
UNSPSC
12352211
Hazard Statement
H302-H315-H318-H335-H351
Target
Glutathione S-transferase
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Metabolic Disease
Smiles
ClC(Br)Cl
Molecular Formula
CHBrCl2
Molecular Weight
163.83
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Pegram RA, et al. Glutathione S-transferase-mediated mutagenicity of trihalomethanes in Salmonella typhimurium: contrasting results with bromodichloromethane off chloroform. Toxicol Appl Pharmacol. 1997 May;144 (1) :183-8.|[2]Chen J, et al. Bromodichloromethane inhibits human placental trophoblast differentiation. Toxicol Sci. 2004 Mar;78 (1) :166-74.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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