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Phenidone (Standard)

CAT: 0804-HY-W010144R-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W010144R-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[1][2]. Phenidone is used as a photographic developer[3].
CAS Number
92-43-3
UNSPSC
12352005
Target
COX; Lipoxygenase
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Smiles
O=C1NN(C2=CC=CC=C2)CC1
Molecular Formula
C9H10N2O
Molecular Weight
162.19
References & Citations
[1]Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035 (2) :206-210.|[2]Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6 (1) :52-58.|[3]Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16 (12) :1583-1587.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards