Phenidone (Standard)

• Description:

  Phenidone, an orally active dual inhibitor of cyclooxygenase (COX) and lipoxygenase (LOX), ameliorates rat paralysis in experimental autoimmune encephalomyelitis. Phenidone is a potent hypotensive agent in the spontaneously hypertensive rat[1][2]. Phenidone is used as a photographic developer[3].

• UNSPSC:

  12352005

• Target:

  COX; Lipoxygenase

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology; Cardiovascular Disease

• Smiles:

  O=C1NN(C2=CC=CC=C2)CC1

• Molecular Formula:

  C9H10N2O

• Molecular Weight:

  162.19

• References & Citations:

  [1]Moon C, et al. Phenidone, a dual inhibitor of cyclooxygenases and lipoxygenases, ameliorates rat paralysis in experimental autoimmune encephalomyelitis by suppressing its target enzymes. Brain Res. 2005;1035 (2) :206-210.|[2]Stern N, et al. The lipoxygenase inhibitor phenidone is a potent hypotensive agent in the spontaneously hypertensive rat. Am J Hypertens. 1993;6 (1) :52-58.|[3]Petrakiev A, et al. Emission spectral analysis using photographic plates treated with a phenidone developer. Talanta. 1969;16 (12) :1583-1587.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [92-43-3]