2-Bromo-4'-fluoroacetophenone

• Description:

  2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.

• Product Name Alternative:

  P-Fluorophenacyl bromide

• UNSPSC:

  12352005

• Hazard Statement:

  H314

• Target:

  DNA/RNA Synthesis

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Purity:

  99.29

• Solubility:

  DMSO : 66.67 mg/mL (ultrasonic)

• Smiles:

  BrCC (C1=CC=C (F) C=C1) =O

• Molecular Formula:

  C8H6BrFO

• Molecular Weight:

  217.04

• Precautions:

  H314

• References & Citations:

  [1]Wender P A, et al. Photoinduced cleavage of DNA by bromofluoroacetophenone–pyrrolecarboxamide conjugates[J]. Bioorganic & medicinal chemistry letters, 2003, 13 (10) : 1763-1766.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  403-29-2