2-Bromo-4'-fluoroacetophenone

• Description :

  2-Bromo-4'-fluoroacetophenone is a photoinduced DNA cleaving agent that serves as a precursor for fluoro-substituted phenyl radicals, generating highly reactive radicals upon illumination to mediate DNA strand breakage.

• Product Name Alternative :

  P-Fluorophenacyl bromide

• UNSPSC :

  12352005

• Hazard Statement :

  H314

• Target :

  DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/DNA Damage

• Field of Research :

  Cancer

• Purity :

  99.29

• Solubility :

  DMSO : 66.67 mg/mL (ultrasonic)

• Smiles :

  BrCC(C1=CC=C(F)C=C1)=O

• Molecular Formula :

  C8H6BrFO

• Molecular Weight :

  217.04

• Precautions :

  H314

• References & Citations :

  [1]Wender P A, et al. Photoinduced cleavage of DNA by bromofluoroacetophenone–pyrrolecarboxamide conjugates[J]. Bioorganic & medicinal chemistry letters, 2003, 13 (10) : 1763-1766.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [403-29-2]