Estradiol 3-methyl ether

• Description:

  Estradiol 3-methyl ether is a synthetic estrogen. Estradiol 3-methyl ether can disrupt microtubule networks in V79 cells with an EC50 of 9 μM, as well as inhibiting cell proliferation. Estradiol 3-methyl ether decreases the serum cholesterol levels and increases body weight loss, which indicates feminizing activity in HFD murine model[1][2].

• Product Name Alternative:

  3-O-Methyl estradiol; 17β-Estradiol 3-methyl ether; 3-Methoxyestradiol

• UNSPSC:

  12352211

• Hazard Statement:

  H302+H312+H332

• Target:

  Biochemical Assay Reagents

• Related Pathways:

  Others

• Field of Research:

  Endocrinology

• Purity:

  99.93

• Smiles:

  C[C@]12CC[C@]3([H])C4=CC=C(OC)C=C4CC[C@@]3([H])[C@]1([H])CC[C@]2([H])O

• Molecular Formula:

  C19H26O2

• Molecular Weight:

  286.41

• Precautions:

  H302+H312+H332

• References & Citations:

  [1]Aizu-Yokota, E., et al., (1995) . Natural estrogens induce modulation of microtubules in Chinese hamster V79 cells in culture. Cancer research, 55 (9), 1863–1868. |[2]R.M. Tomarelli, et al., Bioassay of Hypocholesterolemic Steroids, Journal of Pharmaceutical Sciences, Volume 55, Issue 12, 1966.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound2

• Clinical Information:

  No Development Reported

• CAS Number:

  [1035-77-4]