BPP 5a

• Description :

  BPP 5a is a bradykinin-potentiating peptide with vasorelaxant activity, which is found in Bothrops jararaca venom. BPP 5a is an angiotensin-converting enzyme (ACE) inhibitor with a Ki value of 400 nM. BPP 5a is promising for research of hypertension and cardiovascular diseases[1].

• CAS Number :

  [30505-63-6]

• UNSPSC :

  12352209

• Target :

  Angiotensin Receptor; Peptide-Drug Conjugates (PDCs)

• Related Pathways :

  Antibody-drug Conjugate/ADC Related; GPCR/G Protein

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C([C@H]1NC(CC1)=O)N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C)C(N2[C@@H](CCC2)C(O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O

• Molecular Formula :

  C30H41N7O7

• Molecular Weight :

  611.69

• References & Citations :

  [1]Ianzer D, et al. BPP-5a produces a potent and long-lasting NO-dependent antihypertensive effect. Ther Adv Cardiovasc Dis. 2011 Dec;5 (6) :281-95.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported