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FZ1 peptide

CAT: 0804-HY-P11474Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P11474Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FZ1 peptide is an integrin αvβ3 agonist. FZ1 peptide binds to integrin αvβ3, effectively activates FAK, FAK-dependent AKT and ERK1/2 signaling pathways. FZ1 peptide enhances VEGFC-induced endothelial angiogenesis, accelerates diabetic skin wound healing[1].
UNSPSC
12352209
Target
Akt; ERK; FAK; Integrin
Related Pathways
Cytoskeleton; MAPK/ERK Pathway; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Field of Research
Metabolic Disease
Smiles
O=C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@H]1CC(O)=O)=O)=O)=O)=O)[C@H](CSSC[C@@H](C(O)=O)NC1=O)N
Molecular Formula
C29H49N9O12S2
Molecular Weight
779.88
References & Citations
[1]Wang L, et al. Cyclic Heptapeptide FZ1 Acts as an Integrin αvβ3 Agonist to Facilitate Diabetic Skin Wound Healing by Enhancing Angiogenesis. J Med Chem. 2025 Sep 25;68 (18) :19503-19520.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
ERK1; ERK2; αvβ3

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