PAI-1

• Description:

  PAI-1 is a plasminogen activator inhibitor. PAI-1 is a member of the Ser Protease inhibitor superfamily with antiprotease activity. PAI-1 is the main physiological inhibitor of tissue-type (tPA) and urokinase-type (uPA) plasminogen activators (PAs) [1].

• UNSPSC:

  12352209

• Target:

  Ser/Thr Protease

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Smiles:

  [H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCC(O)=O)C(O)=O)=O)=O)C)=O)CCSC)=O)=O)C

• Molecular Formula:

  C27H47N9O9S

• Molecular Weight:

  673.78

• References & Citations:

  [1]Tang Z, et al. Surface immobilization of a protease through an inhibitor-derived affinity ligand: a bioactive surface with defensive properties against an inhibitor. Chem Commun (Camb) . 2015 Sep 28;51 (75) :14263-6.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  139446-70-1