Oscillamide C (TFA)

• Description:

  Oscillamide C TFA (Compound 2), a ureido-containing cyclic peptide, is a Protein phosphatase 1 (PP1) and Protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.90 and 1.33 μM for PP1 and PP2A, respectively. Oscillamide C TFA can be isolated from the cyanobacteria Planktothrix agardhii and P. rubescens. Oscillamide C TFA can be used for cancers research[1].

• UNSPSC:

  12352209

• Target:

  Phosphatase

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C(O)C(F)(F)F.OC(C=C1)=CC=C1CC[C@@H]2N(C([C@@H](NC([C@](NC([C@@H](CCCCNC([C@@H](NC2=O)CC3=CC=CC=C3)=O)NC(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)([H])[C@@H](C)CC)=O)CCC4=CC=C(C=C4)O)=O)C

• Molecular Formula:

  C51H69F3N10O12

• Molecular Weight:

  1071.15

• References & Citations:

  [1]Sano T, et al. Isolation of new protein phosphatase inhibitors from two cyanobacteria species, Planktothrix spp. J Nat Prod. 2001 Aug;64 (8) :1052-5.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported