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C (avb6) -DOTA (TFA)

CAT: 0804-HY-P6351-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P6351-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C (avb6) -DOTA TFA is a conjugate of the αvβ6 integrin selective peptide ring modified with DOTA chelator. The Lu (III) complex of c (avb6) -DOTA TFA has a comparable affinity for αvβ6 integrin (IC50=0.8 nM) and can be used as a tumor diagnostic[1].
UNSPSC
12352209
Target
Integrin
Type
Peptides
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-avb6-dota-tfa.html
Purity
96.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C(F)(F)F)=O.O=C([C@H]1CCCN1C2=O)N([C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]2CC3=CC=CC=C3)=O)C)=O)CC(C)C)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CC4=CC=CC=C4)=O)CCCCNC(CN5CCN(CCN(CCN(CC5)CC(O)=O)CC(O)=O)CC(O)=O)=O)C
Molecular Formula
C69H102F3N17O20
Molecular Weight
1546.65
References & Citations
[1]Färber S F, et al. Therapeutic radiopharmaceuticals targeting integrin αvβ6[J]. ACS omega, 2018, 3 (2) : 2428-2436.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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