KSL-W

• Description:

  KSL-W is a multifunctional antibacterial peptide with immune regulatory function. KSL-W has a chemotactic effect on neutrophils. KSL-W can induce neutrophil F-actin polymerization dependent on the Gαi protein signaling pathway. KSL-W can inhibit the production of reactive oxygen species (ROS) in neutrophils. KSL-W can be used for research on infection control and inflammation regulation[1].

• UNSPSC:

  12352209

• Target:

  Bacterial; Reactive Oxygen Species (ROS)

• Related Pathways:

  Anti-infection; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Field of Research:

  Infection; Inflammation/Immunology

• Smiles:

  O=C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CNC3=CC=CC=C23)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CCCCN)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N

• Molecular Formula:

  C68H106N16O10

• Molecular Weight:

  1307.67

• References & Citations:

  [1]Williams RL, et al. Antimicrobial decapeptide KSL-W enhances neutrophil chemotaxis and function. Peptides. 2012 Jan;33 (1) :1-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [1206554-01-9]