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LANA

CAT: 0804-HY-P11137Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-P11137Size:1 Each
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Description
LANA is a KSHV latency-associated nuclear antigen. The core function of LANA is to act as an "anchor" for the viral genome, attaching it to the chromatin of the host cell. LANA ensures that the episomal DNA of KSHV replicates together with the host chromosome and is evenly distributed among the daughter cells, thereby maintaining the latent infection of the virus in the cell population. LANA can regulate the transcription of viral and host cell genes, and regulate certain host cell genes to promote cell survival. LANA can be used to study the viral DNA tethering structure[1].
CAS Number
878495-58-0
UNSPSC
12352209
Target
HSV
Related Pathways
Anti-infection
Field of Research
Cancer
Smiles
O=C(N[C@@H](C)C(N1[C@@H](CCC1)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCSC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](C)C(N3[C@@H](CCC3)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CO)C(N[C@@H](CS)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@@H](CCSC)N
Molecular Formula
C95H167N35O29S3
Molecular Weight
2359.75
References & Citations
[1]Schneider WM, et al. Viral DNA tethering domains complement replication-defective mutations in the p12 protein of MuLV Gag. Proc Natl Acad Sci U S A. 2013 Jun 4;110 (23) :9487-92.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

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