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Fulipiftide

CAT: 0804-HY-P10953-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10953-01Size:1 mg
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Description
Fulipiftide is a short peptide derived from pigment epithelium-derived factor (PEDF) . Fulipiftide induces the expansion of nuclear stem cell factor +TSPC by activating ERK2 and STAT3 signaling pathways. Fulipiftide has anti-inflammatory activity and can be used in the study of acute tendon injury[1][2].
CAS Number
2868985-56-0
Product Name Alternative
PSP 29-mer, anti-inflammatory peptide
UNSPSC
12352209
Target
ERK; STAT
Related Pathways
JAK/STAT Signaling; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.38
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
C[C@@H](O)[C@@H](C(N)=O)NC(CNC([C@H](CC1=CN=CN1)NC([C@H]([C@@H](C)CC)NC([C@H](CC(O)=O)NC([C@H]2N(CCC2)C([C@H](CO)NC([C@H](CO)NC([C@H]([C@@H](C)CC)NC([C@H](CC(C)C)NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](NC([C@H](CC(C)C)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@H]([C@@H](C)CC)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCC(O)=O)NC([C@H](C)NC(CNC([C@H](CC(C)C)NC([C@H](CO)NC(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)=O)=O)CC4=CC=C(C=C4)O)=O)CC5=CC=C(C=C5)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C144H227N41O47
Molecular Weight
3284.59
References & Citations
[1]WHO. International Nonproprietary Names for Pharmaceutical Substances (INN), Proposed International Nonproprietary Names: List 132. WHO Drug Information, Vol. 38 , No. 4, 2024.|[2]Ho TC, et al. PEDF-derived peptide promotes tendon regeneration through its mitogenic effect on tendon stem/progenitor cells. Stem Cell Res Ther. 2019 Jan 3;10 (1) :2.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
ERK2; STAT3

Chemical Information

Fulipiftide
CAS Number2868985-56-0
PubChem CID177669090
IUPAC Name(4S)-4-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-acetamido-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]acetyl]amino]propanoyl]amino]-5-[[(2S)-5-amino-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[2-[[(2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl]amino]-2-oxoethyl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-5-oxopentanoic acid
Molecular FormulaC144H227N41O47
Molecular Weight3284.6
XLogP-8.5
Topological Polar Surface Area1410
Hydrogen Bond Donor Count50
Hydrogen Bond Acceptor Count51
Rotatable Bond Count108
Heavy Atom Count232
Formal Charge0
Complexity7680
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC2=CN=CN2)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC5=CN=CN5)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)C
InChI
InChI=1S/C144H227N41O47/c1-20-69(11)110(137(227)174-94(52-80-56-151-64-157-80)120(210)156-59-105(197)179-114(75(17)190)116(146)206)181-132(222)97(55-109(204)205)173-136(226)102-29-26-46-185(102)142(232)101(63-189)178-134(224)99(61-187)177-139(229)111(70(12)21-2)180-131(221)91(49-68(9)10)169-130(220)96(54-108(202)203)172-128(218)93(51-79-32-36-83(194)37-33-79)171-127(217)92(50-78-30-34-82(193)35-31-78)170-126(216)90(48-67(7)8)167-118(208)74(16)160-121(211)84(27-24-44-153-143(147)148)164-129(219)95(53-81-57-152-65-158-81)175-138(228)112(71(13)22-3)183-140(230)113(72(14)23-4)182-135(225)100(62-188)176-124(214)88(40-43-107(200)201)166-141(231)115(76(18)191)184-125(215)85(28-25-45-154-144(149)150)163-122(212)86(38-41-103(145)195)165-123(213)87(39-42-106(198)199)162-117(207)73(15)159-104(196)58-155-119(209)89(47-66(5)6)168-133(223)98(60-186)161-77(19)192/h30-37,56-57,64-76,84-102,110-115,186-191,193-194H,20-29,38-55,58-63H2,1-19H3,(H2,145,195)(H2,146,206)(H,151,157)(H,152,158)(H,155,209)(H,156,210)(H,159,196)(H,160,211)(H,161,192)(H,162,207)(H,163,212)(H,164,219)(H,165,213)(H,166,231)(H,167,208)(H,168,223)(H,169,220)(H,170,216)(H,171,217)(H,172,218)(H,173,226)(H,174,227)(H,175,228)(H,176,214)(H,177,229)(H,178,224)(H,179,197)(H,180,221)(H,181,222)(H,182,225)(H,183,230)(H,184,215)(H,198,199)(H,200,201)(H,202,203)(H,204,205)(H4,147,148,153)(H4,149,150,154)/t69-,70-,71-,72-,73-,74-,75+,76+,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,110-,111-,112-,113-,114-,115-/m0/s1
InChIKey
WKXNKQZYGSNBDJ-VGQQASIRSA-N
Chemical Structure
2D Structure
2D structure of Fulipiftide
CAS: 2868985-56-0
CID: 177669090
Formula: C144H227N41O47
MW: 3284.6
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight3284.6
XLogP3-8.5
Hydrogen Bond Donor Count50
Hydrogen Bond Acceptor Count51
Rotatable Bond Count108
Exact Mass3283.6666584
Monoisotopic Mass3282.6633035
Topological Polar Surface Area1410 Ų
Heavy Atom Count232
Formal Charge0
Complexity7680
Isotope Atom Count0
Defined Atom Stereocenter Count33
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
GTR19133730-01Fulipiftide

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