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GNQWFI

CAT: 0804-HY-P10831-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P10831-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GNQWFI, an anti-Flt1 peptide, is a VEGFR1-specific antagonist. GNQWFI blocks the interaction of VEGFR1 with various VEGFR1 ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF) and inhibits VEGF-induced endothelial cell migration and tube formation. GNQWFI is promising for research of cancer, asthma, and other ocular diseases[1].
CAS Number
853995-60-5
UNSPSC
12352209
Target
VEGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Cardiovascular Disease
Purity
99.45
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC[C@H](C)[C@@H](C(O)=O)NC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CC(N)=O)NC(CN)=O)=O)=O)CC2=CNC3=CC=CC=C23)=O)=O
Molecular Formula
C37H49N9O9
Molecular Weight
763.84
References & Citations
[1]Oh EJ, et al. Synthesis, characterization, and preliminary assessment of anti-Flt1 peptide-hyaluronate conjugate for the treatment of corneal neovascularization. Biomaterials. 2009 Oct;30 (30) :6026-34.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
VEGFR1/Flt-1

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CatalogName
GTR19069604-01GNQWFI

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