Products for Research Use Only

GNQWFI

CAT: 0931-TP2994-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2994-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
853995-60-5
Target
VEGFR
Related Pathways
Angiogenesis, Tyrosine Kinase/Adaptors
Bioactivity
GNQWFI, an anti-Flt1 peptide, functions as a VEGFR1-specific antagonist. It inhibits interactions between VEGFR1 and various ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF), and suppresses VEGF-induced endothelial cell migration and tubulogenesis. GNQWFI holds potential for research in cancer, asthma, and other ocular diseases.
Smiles
C([C@@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H]([C@H](CC)C)C(O)=O)=O)=O)NC([C@@H](NC([C@@H](NC(CN)=O)CC(N)=O)=O)CCC(N)=O)=O)C=2C=3C(NC2)=CC=CC3
Molecular Formula
C37H49N9O9
Molecular Weight
763.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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