Products for Research Use Only
RegisterLogin

Gnidimacrin

CAT: 0804-HY-N9382Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-N9382Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Gnidimacrin is a protein kinase C (PKC) activator. Gnidimacrin inhibits cell growth of human leukemias, stomach cancers and non-small cell lung cancers in vitro, and shows activity against murine leukemias and solid tumors in vivo. Gnidimacrin can be used for leukemias, stomach cancers and non-small cell lung cancers research[1].
CAS Number
60796-70-5
UNSPSC
12352005
Target
PKC
Related Pathways
Epigenetics; TGF-beta/Smad
Field of Research
Cancer
Smiles
C(OC(=O)C1=CC=CC=C1)[C@H]2[C@@]34[C@]5([C@]6([C@](CO)(O6)[C@@H](O)[C@@]7(O)[C@]3([C@]([C@H](C)[C@@H]7OC(=O)C8=CC=CC=C8)([C@H](C)CCCCCC[C@@H](O)[C@@]9(O4)O[C@]5([C@](C(C)=C)(C2)O9)[H])[H])[H])[H])[H]
Molecular Formula
C44H54O12
Molecular Weight
774.90
References & Citations
[1]Yoshida M, et al. Antitumor activity of daphnane-type diterpene gnidimacrin isolated from Stellera chamaejasme L. Int J Cancer. 1996 Apr 10;66 (2) :268-73.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Gnidimacrin

Gnidimacrin has been reported in Stellera chamaejasme and Pimelea ligustrina with data available.

CAS Number60796-70-5
PubChem CID44575159
IUPAC Name[(1R,2S,4S,5R,6S,7S,9R,10S,11S,12S,13S,14S,15R,22R,25R)-12-benzoyloxy-10,11,22-trihydroxy-9-(hydroxymethyl)-13,15-dimethyl-4-prop-1-en-2-yl-8,24,26,27-tetraoxaheptacyclo[12.10.1.14,23.15,23.01,6.07,9.011,25]heptacosan-2-yl]methyl benzoate
Molecular FormulaC44H54O12
Molecular Weight774.9
XLogP6
Topological Polar Surface Area174
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count12
Rotatable Bond Count9
Heavy Atom Count56
Formal Charge0
Complexity1540
SMILES
C[C@@H]1CCCCCC[C@H](C23O[C@@H]4[C@@H]5[C@H]6[C@](O6)([C@H]([C@]7([C@@H]([C@@H]1[C@@H]([C@@H]7OC(=O)C8=CC=CC=C8)C)[C@@]5(O2)[C@@H](C[C@]4(O3)C(=C)C)COC(=O)C9=CC=CC=C9)O)O)CO)O
InChI
InChI=1S/C44H54O12/c1-24(2)40-21-29(22-51-37(47)27-16-10-7-11-17-27)43-32-35(40)54-44(55-40,56-43)30(46)20-14-6-5-9-15-25(3)31-26(4)34(52-38(48)28-18-12-8-13-19-28)42(50,33(31)43)39(49)41(23-45)36(32)53-41/h7-8,10-13,16-19,25-26,29-36,39,45-46,49-50H,1,5-6,9,14-15,20-23H2,2-4H3/t25-,26+,29+,30-,31+,32-,33-,34+,35-,36+,39-,40+,41+,42-,43-,44?/m1/s1
InChIKey
SSXCVTWCXHGTLK-HPSSUOODSA-N
Chemical Structure
2D Structure
2D structure of Gnidimacrin
CAS: 60796-70-5
CID: 44575159
Formula: C44H54O12
MW: 774.9
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight774.9
XLogP36
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count12
Rotatable Bond Count9
Exact Mass774.36152715
Monoisotopic Mass774.36152715
Topological Polar Surface Area174 Ų
Heavy Atom Count56
Formal Charge0
Complexity1540
Isotope Atom Count0
Defined Atom Stereocenter Count15
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
AR-G02719-01Gnidimacrin

Popular Products