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Gnidimacrin

CAT: 0931-T69009-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T69009-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
60796-70-5
Target
Others
Related Pathways
Others
Bioactivity
Gnidimacrin activated HIV-1 replication and killed persistently-infected cells at picomolar concentrations. In addition to its potential to purge HIV-1 from latently infected cells, gnidimacrin potently inhibited a panel of HIV-1 R5 virus infection of peripheral blood mononuclear cells (PBMCs) at an average concentration lower than 10 pM. These results suggest that gnidimacrin could activate latent HIV-1, specifically kill HIV-1 persistently infected cells, and inhibit R5 viruses at picomolar concentrations
Smiles
C(OC(=O)C1=CC=CC=C1)[C@H]2[C@@]34[C@]5([C@]6([C@](CO)(O6)[C@@H](O)[C@@]7(O)[C@]3([C@]([C@H](C)[C@@H]7OC(=O)C8=CC=CC=C8)([C@H](C)CCCCCC[C@@H](O)[C@@]9(O4)O[C@]5([C@](C(C)=C)(C2)O9)[H])[H])[H])[H])[H]
Molecular Formula
C44H54O12
Molecular Weight
774.89
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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