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(rac) -Poriol

CAT: 0804-HY-N9086ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N9086ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(rac) -Poriol (5,7,4'-Trihydroxy-6-methylflavanone) exhibits antioxidant activity, and scavenges free radical DPPH with an IC50 of 0.18 µg/mL. (rac) -Poriol inhibits the LPS -induced NO generation in RAW264.7 (98.35% inhibition rate at 10 μM), and exhibits anti-inflammatory activity. (rac) -Poriol exhibits good binding affinity with iNOS, COX-1, COX-2, TNF-α, and IL-1β[1].
CAS Number
70460-58-1
Product Name Alternative
5,7,4'-Trihydroxy-6-methylflavanone
UNSPSC
12352005
Target
COX; Interleukin Related; NO Synthase
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C1C2=C(C(C)=C(C=C2OC(C1)C3=CC=C(C=C3)O)O)O
Molecular Formula
C16H14O5
Molecular Weight
286.28
References & Citations
[1]Sucahyo A, et al. Flavanones from ethyl acetate fraction of Caesalpinia sappan heartwood as anti-inflammatory and antioxidant: Isolation, in-vitro, and in-silico approach[C]//AIP Conference Proceedings. AIP Publishing, 2024, 3055 (1) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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