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D-α-Tocopherylquinone (Standard)

CAT: 0804-HY-N2853RSize: 1 EachDry Ice: NoHazardous: No
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Description
D-α-Tocopherylquinone (α-Tocopherylquinone) (Standard) is the analytical standard of D-α-Tocopherylquinone. This product is intended for research and analytical applications. D-α-Tocopherylquinone is a quinone, can be isolated from Phaeodactylum tricornutum. D-α-Tocopherylquinone is an oxidation product of α-Tocopherol (vitamin E) . D-α-Tocopherylquinone can act as an anticoagulant and as an antioxidant. D-α-Tocopherylquinone reduces cellular oxidative damage produced by oxidized lipids. D-α-Tocopherylquinone binds to a liver cytosolic protein with a molecular mass of about 40 kDa. D-α-Tocopherylquinone binds to glurathione-S-transferase (GST) and can be transported to the site of metabolism or excreted in the bile[1][2][3].
CAS Number
7559-04-8
Product Name Alternative
α-Tocopherylquinone (Standard)
UNSPSC
12352211
Target
Reactive Oxygen Species (ROS) ; Reference Standards
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Field of Research
Others
Smiles
CC(C)CCC[C@@H](C)CCC[C@@H](C)CCC[C@@](C)(O)CCC1=C(C(C(C)=C(C)C1=O)=O)C
Molecular Formula
C29H50O3
Molecular Weight
446.71
References & Citations
[1]K Shimazaki, et al. Studies on electron transfer systems in the marine diatom Phaeodactylum tricornutum. II. Identification and determination of quinones, cytochromes, and flavins. J Biochem. 1978 Jun;83 (6) :1639-42.|[2]M K Horwitt. Vitamin E: a reexamination. Am J Clin Nutr. 1976 May;29 (5) :569-78.|[3]Arita, M., et al., (1998) . Binding of alpha-tocopherylquinone, an oxidized form of alpha-tocopherol, to glutathione-S-transferase in the liver cytosol. FEBS letters, 436 (3), 424–426.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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