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Maltotetraose

CAT: 0804-HY-N2464-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N2464-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Maltotetraose can serve as a substrate for enzyme-linked assays to measure amylase activity in biological fluids. Maltotetraose has oral active, and reduces TNF-α-induced inflammatory responses by inhibiting NF-κB activity and decreasing ICAM-1 expression. Maltotetraose also inhibits PDGF-induced vascular smooth muscle cell migration and neovascularization. Additionally, Maltotetraose derivatives can function as probes for detecting bacterial infections by targeting the maltodextrin transporter. With good long-term safety, Maltotetraose holds promise for research in atherosclerosis-related diseases[1][2][3][4].
CAS Number
34612-38-9
Product Name Alternative
Amylotetraose; Fujioligo 450; α-1,4-Tetraglucose
UNSPSC
12352005
Hazard Statement
H315
Target
Bacterial; Endogenous Metabolite; Integrin; NF-κB; TNF Receptor
Related Pathways
Anti-infection; Apoptosis; Cytoskeleton; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Purity
99.88
Solubility
H2O : 125 mg/mL (ultrasonic)
Smiles
OC[C@@H](O[C@H](O[C@@]([C@H](O)CO)([H])[C@H](O)[C@@H](O)C=O)[C@H](O)[C@H]1O)[C@@]1([H])O[C@H]2O[C@@H]([C@@H](O[C@@]3([H])O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)[C@H](O)[C@H]2O)CO
Molecular Formula
C24H42O21
Molecular Weight
666.58
Precautions
H315
References & Citations
[1]Whitlow KJ, et al. Maltotetraose as a substrate for enzyme-coupled assay of amylase activity in serum and urine. Clin Chem. 1979 Mar;25 (3) :481-3.|[2]Shin SY, et al. Inhibition of PDGF-induced migration and TNF-α-induced ICAM-1 expression by maltotetraose from bamboo stem extract (BSE) in mouse vascular smooth muscle cells. Mol Nutr Food Res. 2016 Sep;60 (9) :2086-97.|[3]Matsumoto S, et al. Maltosyltrehalose Syrup: Bacterial reverse mutation test, and 90-day feeding and 90-day repeated oral dose toxicity studies in rats[J]. Fundamental Toxicological Sciences, 2020, 7 (3) : 141-152.|[4]Zlitni A, et al. Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections. Nat Commun. 2020 Mar 6;11 (1) :1250.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite

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