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Clavicoronic acid

CAT: 0804-HY-N14957Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N14957Size:1 Each
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Description
Clavicoronic acid is an avian myeloblastosis virus and Moloney murine leukemia virus reverse transcriptases inhibitor with Ki values of 130, 68 µM, respectively. Clavicoronic acid inhibits the multiplication of vesicular stomatitis virus by interfering with this virus's RNA-directed RNA-polymerase. Clavicoronic acid shows no cytotoxicity[1].
CAS Number
139748-98-4
UNSPSC
12352211
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
CC1=C(C(C(O)=O)=O)C(C=O)=C[C@@]2([H])[C@]1([H])CC(C)(C)C2
Molecular Formula
C15H18O4
Molecular Weight
262.30
References & Citations
[1]Erkel G, et al. Antibiotics from basidiomycetes. XLI. Clavicoronic acid, a novel inhibitor of reverse transcriptases from Clavicorona pyxidata (Pers. ex Fr.) Doty. J Antibiot (Tokyo) . 1992 Jan;45 (1) :29-37.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported