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Pochonin D

CAT: 0804-HY-N14780Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N14780Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pochonin D ((+) -Pochonin D) is an inhibitor of heat shock protein 90 (Hsp90) with antiviral and anti-inflammatory activities. Pochonin D inhibits Hsp90, affecting the homeostasis, folding, and assembly processes of viral proteins, reducing the replication ability of the virus. Pochonin D reduces the infiltration of inflammatory cells and the secretion of inflammatory cytokines such as TNF-α and IL-1β, alleviating the inflammatory response. Pochonin D is promising for research of Human rhinoviruses (HRV) infections and cancers[1].
CAS Number
544712-82-5
Product Name Alternative
(+) -Pochonin D
UNSPSC
12352101
Target
Enterovirus; HSP; Interleukin Related
Related Pathways
Anti-infection; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection; Inflammation/Immunology
Smiles
ClC1=C2C(C(O[C@@H](C/C=C/CC/C=C/C(C2)=O)C)=O)=C(C=C1O)O
Molecular Formula
C18H19ClO5
Molecular Weight
350.79
References & Citations
[1]Song JH, et al. Antiviral and Anti-Inflammatory Activities of Pochonin D, a Heat Shock Protein 90 Inhibitor, against Rhinovirus Infection. Biomol Ther (Seoul) . 2018 Nov 1;26 (6) :576-583.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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